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Shelley Research Lab

Shelley Research Lab

Just The Science

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Latest News

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April 4, 2024: Research Specialist Abby Ross receives Honorable Mention in the NSF Graduate Research Fellowship Program
February 29, 2024: PhD Candidate Julia Danischewski Wins 2024 ASMS Graduate Student Award
October 13, 2023: Prof. Shelley Wins FACSS Innovation Award at SciX 2023
October 10, 2023: PhD Candidate Julia Danischewski Wins Student Poster Award at SciX 2023
July 28, 2023: Student Chapter of the SAS Wins 2023 William J. Poehlman Award

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Our Research

Prof. Jacob Shelley’s research in the Department of Chemistry and Chemical Biology at Rensselaer Polytechnic Institute centers on the development of new hardware and software tools for mass spectrometry and optical spectroscopy, which enable rapid and sensitive detection and identification of analytes in complex matrices. Specifically, our group approaches these tasks through development, fundamental characterization, and application of instrumentation.

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Instrument Development

Our aim is to develop an ionization source which operates at atmospheric pressure that can provide molecular, structural, and atomic information of species present on a sample surface. Overall, this research addresses a major focus of modern analytical chemistry – rapid, in situ detection of relevant compounds without the need for sample modification or a priori information of sample constituents.

Fundamental Characterization

Advanced imaging and ion manipulation techniques are leveraged to understand the transport of gaseous species from an ion source into a mass spectrometer. Plasma tuning allows for unique gas-phase ion-ion and ion-molecule chemistry to rapidly modify inert substances.

Applications

These novel methods of analysis are needed in a wide range of areas including environmental monitoring, astrobiology, forensic analysis, drug development, and chemical synthesis.

Our Team

The Shelley Research Lab at Rensselaer Polytechnic Institute includes talented graduate and undergraduate students, research specialists, and interns with diverse experience and research interests.

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Recent Publications

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Manipulation of Gaseous Ions with Acoustic Fields at Atmospheric Pressure

Yi You, Julia Danischewski, Brian Molnar, Jens Riedel and Jacob T. Shelley

Journal of the American Chemical Society (accepted).

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Characterization of a Low-Temperature Plasma (LTP) Ambient Ionization Source Using Temporally Resolved Monochromatic Imaging Spectrometry

George C.-Y. Chan, Carsten Engelhard, Joshua S. Wiley, Ayanna U. Shoulds, R. Graham Cooks, Gary M. Hieftje and Jacob T. Shelley

Applied Spectroscopy (2023). 77 (8): 940-956.

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Home: Publications

Gary M. Hieftje: 80+ Years of Life, 53+ Years of Spectroscopy Innovation, and Many Lifetimes of Inspiration

Guest Editor: Jacob T. Shelley

Applied Spectroscopy (2023). 77 (8): 787-969.

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Home: Publications

Spectral Properties and Stability of Selected Carotenoid and Chlorophyll Compounds in Different Solvent Systems

Eyosias L. Ashenafi, Marianne C. Nyman, Jacob T. Shelley and Neil S. Mattson

Food Chemistry Advances (2023). 2: 100178.

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